SIMPLE AND CONDENSED BETA-LACTAMS .17. MONOBACTAMS ACYLATED WITH ISOXAZOLEACETIC AND ISOXAZOLECARBOXYLIC ACIDS

被引：0

作者：

NAGY, J

NYITRAI, J

KAJTARPEREDY, M

机构：

[1] TECH UNIV BUDAPEST,DEPT ORGAN CHEM,H-1521 BUDAPEST,HUNGARY

[2] HUNGARIAN ACAD SCI,CENT RES INST CHEM,H-1525 BUDAPEST,HUNGARY

来源：

LIEBIGS ANNALEN DER CHEMIE | 1993年 / 08期

关键词：

AZTREONAM ANALOGS; CARUMONAM ANALOGS; BETA-LACTAMS; ANTIBIOTICS;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Analogues of aztreonam (1a) and carumonam (1b) were prepared by acylation of 3-aminomonobactamic acid derivatives with several new and known isoxazoleacetic and isoxazolecarboxylic acid derivatives 3-10. None of the resulting new monobactams 11-18, 41a, 41b, and 54a exhibited any significant antibacterial activity.

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页码：815 / 821

页数：7

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