ON ASYMMETRY OF LAMBDA INTEGRATION SITES

被引：51

作者：

GUERRINI, F

机构：

[1] Massachusetts Institute of Technology Cambridge, MA

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1969年 / 46卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0022-2836(69)90194-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This work suggests that the attachment regions of Escherichia coli and λ do not carry identical recognition sites. This hypothesis is consequent to an analysis of the lysogenization pattern of the bacteriophages λdg and λ. A new λ particle has been isolated in order to test further this formal proposal. This particle is capable of co-transducing the bacterial markers gal and bio (λdgb). The analysis of the lysogenization pattern of λdgb confirms and extends the suggested dissimilarity of E. coli and λ recognition sites. Another proposal is made, namely, that the excision of the λ prophage is not a simple reversal of the integration process. © 1969.

引用

页码：523 / &

共 27 条

[1]

ARBER W., 1957, SCHWEIZ ZEITSCHR ALLG PATH U BAKT, V20, P659

[2]

ARBER W., 1958, ARCH SCI [GENEVE], V11, P259

[3] POLYLYSOGENY FOR BACTERIOPHAGE-LAMBDA [J].