PHOTOCHEMICAL MODIFICATION OF GLYCINE DIPEPTIDES

被引：29

作者：

ELAD, D

SPERLING, J

机构：

[1] Department of Chemistry, Weizmann Institute of Science, Rehovoth

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1969年 / 11期

关键词：

D O I：

10.1039/j39690001579

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The acetone-initiated photochemical alkylation of protected glycylglycine, glycylalanine, and glycyl-leucine dipeptide methyl esters with isobutene, but-1-ene, and toluene is described. The reactions lead to the preferential conversion of the glycine residue to leucine, norleucine, or phenylalanine, respectively, in yields of up to 60%. A free-radical chain mechanism is proposed for these reactions.

引用

页码：1579 / &

共 30 条

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