PHOTOCHEMICAL MODIFICATION OF GLYCINE DIPEPTIDES

被引：29
作者：
ELAD, D
SPERLING, J
机构：
[1] Department of Chemistry, Weizmann Institute of Science, Rehovoth
来源：
JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1969年 / 11期
关键词：
D O I：
10.1039/j39690001579
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The acetone-initiated photochemical alkylation of protected glycylglycine, glycylalanine, and glycyl-leucine dipeptide methyl esters with isobutene, but-1-ene, and toluene is described. The reactions lead to the preferential conversion of the glycine residue to leucine, norleucine, or phenylalanine, respectively, in yields of up to 60%. A free-radical chain mechanism is proposed for these reactions.
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页码：1579 / &
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