A THREONINE TO ALANINE EXCHANGE AT POSITION-40 OF TET REPRESSOR ALTERS THE RECOGNITION OF THE 6TH BASE PAIR OF TET OPERATOR FROM GC TO AT

被引：41
作者：
ALTSCHMIED, L
BAUMEISTER, R
PFLEIDERER, K
HILLEN, W
机构：
来源：
EMBO JOURNAL | 1988年 / 7卷 / 12期
关键词：
D O I：
10.1002/j.1460-2075.1988.tb03290.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：4011 / 4017
页数：7
相关论文
共 36 条
[21]   CONSTRUCTION OF AN ESCHERICHIA-COLI STRAIN OVERPRODUCING THE TN10-ENCODED TET REPRESSOR AND ITS USE FOR LARGE-SCALE PURIFICATION [J].
OEHMICHEN, R ;
KLOCK, G ;
ALTSCHMIED, L ;
HILLEN, W .
EMBO JOURNAL, 1984, 3 (03) :539-543
[22]   NUCLEOTIDE-SEQUENCE OF THE REPRESSOR GENE OF THE TN10 TETRACYCLINE RESISTANCE DETERMINANT [J].
POSTLE, K ;
NGUYEN, TT ;
BERTRAND, KP .
NUCLEIC ACIDS RESEARCH, 1984, 12 (12) :4849-4863
[23]   AUTOREGULATION AND FUNCTION OF A REPRESSOR IN BACTERIOPHAGE-LAMBDA [J].
PTASHNE, M ;
BACKMAN, K ;
HUMAYUN, MZ ;
JEFFREY, A ;
MAURER, R ;
MEYER, B ;
SAUER, RT .
SCIENCE, 1976, 194 (4261) :156-161
[24]   PLASMID VECTORS FOR HIGH-EFFICIENCY EXPRESSION CONTROLLED BY THE PL PROMOTER OF COLIPHAGE-LAMBDA [J].
REMAUT, E ;
STANSSENS, P ;
FIERS, W .
GENE, 1981, 15 (01) :81-93
[25]  
Rickwood D., 1982, GEL ELECTROPHORESIS, P117
[26]   A BIDIRECTIONALLY ACTIVE SIGNAL FOR TERMINATION OF TRANSCRIPTION IS LOCATED BETWEEN TETA AND ORFL ON TRANSPOSON TN10 [J].
SCHOLLMEIER, K ;
GARTNER, D ;
HILLEN, W .
NUCLEIC ACIDS RESEARCH, 1985, 13 (12) :4227-4237
[27]  
SHINE J, 1974, Proceedings of the National Academy of Sciences of the United States of America, V71, P1342, DOI 10.1073/pnas.71.4.1342
[28]   NUCLEOTIDE-SEQUENCE OF THE REPRESSOR GENE OF THE RA1 TETRACYCLINE RESISTANCE DETERMINANT - STRUCTURAL AND FUNCTIONAL COMPARISON WITH 3 RELATED TET REPRESSOR GENES [J].
UNGER, B ;
KLOCK, G ;
HILLEN, W .
NUCLEIC ACIDS RESEARCH, 1984, 12 (20) :7693-7703
[29]   NUCLEOTIDE-SEQUENCE OF THE GENE, PROTEIN-PURIFICATION AND CHARACTERIZATION OF THE PSC101-ENCODED TETRACYCLINE RESISTANCE-GENE-REPRESSOR [J].
UNGER, B ;
BECKER, J ;
HILLEN, W .
GENE, 1984, 31 (1-3) :103-108
[30]   HYBRIDIZATION OF SYNTHETIC OLIGODEOXYRIBONUCLEOTIDES TO PHI-CHI-174 DNA - EFFECT OF SINGLE BASE PAIR MISMATCH [J].
WALLACE, RB ;
SHAFFER, J ;
MURPHY, RF ;
BONNER, J ;
HIROSE, T ;
ITAKURA, K .
NUCLEIC ACIDS RESEARCH, 1979, 6 (11) :3543-3557
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