A THREONINE TO ALANINE EXCHANGE AT POSITION-40 OF TET REPRESSOR ALTERS THE RECOGNITION OF THE 6TH BASE PAIR OF TET OPERATOR FROM GC TO AT

被引:41
作者
ALTSCHMIED, L
BAUMEISTER, R
PFLEIDERER, K
HILLEN, W
机构
关键词
D O I
10.1002/j.1460-2075.1988.tb03290.x
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:4011 / 4017
页数:7
相关论文
共 36 条
[1]   OVERLAPPING DIVERGENT PROMOTERS CONTROL EXPRESSION OF TN10 TETRACYCLINE RESISTANCE [J].
BERTRAND, KP ;
POSTLE, K ;
WRAY, LV ;
REZNIKOFF, WS .
GENE, 1983, 23 (02) :149-156
[2]   CONSTRUCTION OF A SINGLE-COPY PROMOTER VECTOR AND ITS USE IN ANALYSIS OF REGULATION OF THE TRANSPOSON-TN10 TETRACYCLINE RESISTANCE DETERMINANT [J].
BERTRAND, KP ;
POSTLE, K ;
WRAY, LV ;
REZNIKOFF, WS .
JOURNAL OF BACTERIOLOGY, 1984, 158 (03) :910-919
[3]   CONSTRUCTION AND CHARACTERIZATION OF NEW CLONING VEHICLES .2. MULTIPURPOSE CLONING SYSTEM [J].
BOLIVAR, F ;
RODRIGUEZ, RL ;
GREENE, PJ ;
BETLACH, MC ;
HEYNEKER, HL ;
BOYER, HW ;
CROSA, JH ;
FALKOW, S .
GENE, 1977, 2 (02) :95-113
[4]   CONSTRUCTION AND CHARACTERIZATION OF AMPLIFIABLE MULTICOPY DNA CLONING VEHICLES DERIVED FROM P15A CRYPTIC MINIPLASMID [J].
CHANG, ACY ;
COHEN, SN .
JOURNAL OF BACTERIOLOGY, 1978, 134 (03) :1141-1156
[5]   CLONING AND EXPRESSION OF THE ACINETOBACTER-CALCOACETICUS MUTAROTASE GENE IN ESCHERICHIA-COLI [J].
GATZ, C ;
ALTSCHMIED, J ;
HILLEN, W .
JOURNAL OF BACTERIOLOGY, 1986, 168 (01) :31-39
[6]   CONSTITUTIVE EXPRESSION OF TETRACYCLINE RESISTANCE MEDIATED BY A TN10-LIKE ELEMENT IN HAEMOPHILUS-PARAINFLUENZAE RESULTS FROM A MUTATION IN THE REPRESSOR GENE [J].
HEUER, C ;
HICKMAN, RK ;
CURIALE, MS ;
HILLEN, W ;
LEVY, SB .
JOURNAL OF BACTERIOLOGY, 1987, 169 (03) :990-994
[7]   DOMINANT NEGATIVE MUTATIONS IN THE TN10 TET REPRESSOR - EVIDENCE FOR USE OF THE CONSERVED HELIX-TURN-HELIX MOTIF IN DNA-BINDING [J].
ISACKSON, PJ ;
BERTRAND, KP .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (18) :6226-6230
[8]   DYNAMICS OF REPRESSOR OPERATOR RECOGNITION - THE TN10-ENCODED TETRACYCLINE RESISTANCE CONTROL [J].
KLEINSCHMIDT, C ;
TOVAR, K ;
HILLEN, W ;
PORSCHKE, D .
BIOCHEMISTRY, 1988, 27 (04) :1094-1104
[9]   HETEROLOGOUS REPRESSOR-OPERATOR RECOGNITION AMONG 4 CLASSES OF TETRACYCLINE RESISTANCE DETERMINANTS [J].
KLOCK, G ;
UNGER, B ;
GATZ, C ;
HILLEN, W ;
ALTENBUCHNER, J ;
SCHMID, K ;
SCHMITT, R .
JOURNAL OF BACTERIOLOGY, 1985, 161 (01) :326-332
[10]   EXPRESSION, PURIFICATION AND OPERATOR BINDING OF THE TRANSPOSON TN1721-ENCODED TET REPRESSOR [J].
KLOCK, G ;
HILLEN, W .
JOURNAL OF MOLECULAR BIOLOGY, 1986, 189 (04) :633-641