NOVEL CYTOCIDAL COMPOUNDS, OXOPROPALINES FROM STREPTOMYCES SP G324-PRODUCING LAVENDAMYCIN .2. PHYSICOCHEMICAL PROPERTIES AND STRUCTURE ELUCIDATIONS

被引：22

作者：

ABE, N

ENOKI, N

NAKAKITA, Y

UCHIDA, H

NAKAMURA, T

MUNEKATA, M

机构：

[1] Pharmaceutical Research Laboratories, Sapporo Breweries, Ltd., Shizuoka 425, 10 Okatohme, Yaizu

来源：

JOURNAL OF ANTIBIOTICS | 1993年 / 46卷 / 11期

关键词：

D O I：

10.7164/antibiotics.46.1678

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Novel cytocidal compounds designated oxopropalines A, B, D, E and G were isolated from the fermentation of an actinomycete named Streptomyces sp. G324, a strain that also produced an antitumor antibiotic, lavendamycin. All these compounds possessed a beta-carboline chromophore. The structures of the oxopropalines were elucidated by several NMR spectral analyses and other spectroscopic experiments.

引用

页码：1678 / 1686

页数：9

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[1] NOVEL CYTOCIDAL COMPOUNDS, OXOPROPALINES FROM STREPTOMYCES SP G324-PRODUCING LAVENDAMYCIN .1. TAXONOMY OF THE PRODUCING ORGANISM, FERMENTATION, ISOLATION AND BIOLOGICAL-ACTIVITIES [J].