In vitro antioxidant activity of methanol extract of rhizomes of Curculigo orchioides Gaertn

Methanol extract of Curculigo orchioides was screened for in- vitro antioxidant activity using DPPH assay, superoxide scavenging, nitric oxide scavenging, determination of reducing power and in-vitro lipid peroxidation. Methanol extract was found to be extremely effective in scavenging superoxide radical (IC50 29.28 mu g/ml) whereas activity was moderate in scavenging DPPH radical (IC50 105.94 mu g/ml), nitric oxide radical (IC50 90.96 mu g/ml) and in inhibition of lipid peroxidation (IC50 94.78 ig/ml). Methanol extract showed different levels of antioxidant activities in tested models. It also supported anti oxidant activity by showing significant reducing power. Further HPTLC finger print profile of the methanol extract was established to facilitate its identification and characterization. Present study demonstrated antioxidant activity of methanol extract of Curculigo orchioides in-vitro.