CHINESE POPULATION-DATA ON 3 TETRAMERIC SHORT TANDEM REPEAT LOCI - HUMTHO1, TPOX, AND CSF1PO - DERIVED USING MULTIPLEX PCR AND MANUAL TYPING

被引：53
作者：
HUANG, NE
SCHUMM, J
BUDOWLE, B
机构：
[1] FED BUR INVEST ACAD, CTR FORENS SCI RES & TRAINING, QUANTICO, VA 22135 USA
[2] CRIMINAL INVEST BUR, DNA LAB, TAIPEI, TAIWAN
[3] PROMEGA CORP, MADISON, WI 53711 USA
来源：
FORENSIC SCIENCE INTERNATIONAL | 1995年 / 71卷 / 02期
关键词：
CHINESE; POPULATION DATABASES; STR; HARDY-WEINBERG EXPECTATIONS; LINKAGE EQUILIBRIUM; POLYMERASE CHAIN REACTION; PCR;
D O I：
10.1016/0379-0738(94)01646-M
中图分类号：
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号：
0301 ; 10 ;
摘要：
Allele and genotype frequencies for three tetrameric short tandem repeat (STR) loci were determined in a Chinese sample population using multiplex polymerase chain reaction (PCR), electrophoresis of the PCR products in DNA sequencing gels and subsequent detection by silver staining. The loci are HUMTHO1, TPOX, and CSF1PO. All loci meet Hardy-Weinberg expectations, In addition, there is no evidence for association of alleles among the three loci. The allelic frequency data can be used in human identity testing to estimate the frequency of a multiple STR locus DNA profile in the Chinese population.
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页码：131 / 136
页数：6
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