Role of melatonin in cancer treatment

被引：0

作者：

Escames, Germaine ^{[1
,2
,3
]}

Acuna-Castroviejo, Dario ^{[1
,2
,3
]}

Fernandez-Gila, Beatriz, I ^{[1
]}

Guerra-Libreroa, Ana ^{[1
]}

Floridol, Javier ^{[1
]}

Martinez-Ruiz, Laura ^{[1
]}

Santana, Cesar ^{[1
]}

机构：

[1] Univ Granada, Ctr Invest Biomed, Parque Tecnol Ciencias Salud,Ave Conocimiento S-N, Granada 18100, Spain

[2] Univ Granada, Fac Med, Dept Fisiol, Granada, Spain

[3] Ibs Granada, CIBERFES, Hosp Campus Salud, Granada 18016, Spain

来源：

APPROACHES TO AGING CONTROL | 2018年 / 22期

关键词：

melatonin; cancer; apoptosis; antioxidant; angiogenesis; estrogen signaling pathway; metastasis;

D O I：

暂无

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Melatonin is a natural substance ubiquitous in distribution and present in almost all species ranging from unicellular organisms to humans. Melatonin is synthesized not only in the pineal gland but also in most tissues where it may play a cytoprotective function via paracrine or autocrine effects. Melatonin is effective in suppressing neoplastic growth in a variety of tumors and as an adjuvant therapy, it can be beneficial in treating cancer patients. The aim of this report is to summarize the possible mechanisms involved in melatonin oncostasis and to review what is known about the clinical application in cancer patients.

引用

页码：47 / 61

页数：15

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