ORGANIZATION OF THE IMMUNE-RESPONSE GENES

被引：142
作者：
UHR, JW
CAPRA, JD
VITETTA, ES
COOK, RG
机构：
来源：
SCIENCE | 1979年 / 206卷 / 4416期
关键词：
D O I：
10.1126/science.113876
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The / region of the major histocompatibility complex contains immune response genes that display considerable polymorphism; that is, there are many alleles at each locus. These genes regulate the immune response to antigen by mediating intercellular communication among lymphoreticular cells. An analysis of the primary structure of the products of two subregions of / (I-A, I-E/C) was undertaken in order to understand the genetic organization of the region, the evolution of the genes and, eventually, their function.
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页码：292 / 297
页数：6
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