A NEW FAMILY OF 5-CARBON IMINOALDITOLS WHICH ARE POTENT GLYCOSIDASE INHIBITORS

被引：79

作者：

BERNOTAS, RC ^{[1
]}

PAPANDREOU, G ^{[1
]}

URBACH, J ^{[1
]}

GANEM, B ^{[1
]}

机构：

[1] CORNELL UNIV,DEPT CHEM,BAKER LAB,ITHACA,NY 14853

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 24期

关键词：

D O I：

10.1016/S0040-4039(00)97405-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of 1,5-dideoxy-1,5-imino-D-xylitol 2 (and the enantiomeric iminoalditols 3 and 4) is described. Alditol 2 compares favorably with 1-deoxynojirimycin 1 as a potent inhibitor of β-glucosidase. © 1990.

引用

页码：3393 / 3396

页数：4

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