PRIMARY ANORECTAL MALIGNANT-MELANOMA

被引:7
作者
MIYAHARA, M
SAITO, T
SATO, K
KAKETANI, K
YOSHIDA, T
INOMATA, M
KOBAYASHI, M
YOSHIKAWA, K
机构
[1] The First Department of Surgery, Medical College of Oita, Oita, 879-56, 1-1 Idaigaoka Hasama-machi, Oita-gun
[2] Tomachidai Hospital, Oita
来源
SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY | 1992年 / 22卷 / 02期
关键词
MALIGNANT MELANOMA; ANORECTAL TUMOR; IMMUNOCHEMOTHERAPY;
D O I
10.1007/BF00311345
中图分类号
R61 [外科手术学];
学科分类号
摘要
A case of primary anorectal malignant melanoma seen in a 46 year old woman is presented herein. Her most marked symptoms were bloody stools and anal pain. Endoscopic examination indicated a tumor with ulceration but without pigmentation in the anorectal region. Histologic examination of the biopsied specimens showed spindle-shaped cells with atypia proliferating in a bandlike arrangement, as in leiomyosarcoma. An abdominoperineal resection was done and detailed histological examination of the tumor confirmed the nature of the tumor to be malignant melanoma. The postoperative immunochemotherapy consisted of Dimetyl-Triazeno-Imidasole-Carboxamide (DTIC), Amino-Methyl-Pyrimidinyl-Methyl-Chlorethyl-Nitrosourea-Hydrochloride (ACNU), Vincristine (VCR) and OK-432. The patient has been well without recurrence for fifteen months following her operation through the continuous administration of these agents.
引用
收藏
页码:171 / 175
页数:5
相关论文
共 13 条
[1]  
Mason J.K., Helwig E.B., Anorectal melanoma, Cancer, 19, pp. 39-50, (1966)
[2]  
Pack G.T., Oropeza R., A comparative study of melanoma and epidermoid carcinoma of the anal canal: A review of 20 melanomas and 29 epidermoid carcinomas, Dis Colon Rectum, 10, pp. 161-176, (1967)
[3]  
Remigio P.A., Der B.K., Fovsberg R.T., Anorectal melanoma, Dis Colon Rectum, 19, pp. 350-365, (1976)
[4]  
Braasted F.W., Dockert M.B., Dixon C.F., Melanoepithelioma of the anus and rectum, Surgery, 25, pp. 82-90, (1949)
[5]  
Wanebo H.J., Woodruff J.M., Farr G.H., Quan S.H., Anorectal melanoma, Cancer, 47, pp. 1891-1900, (1981)
[6]  
Cooper P.H., Mills S.E., Allen, Malignant melanoma of the anus. Report of 12 patients and analysis of 255 additional cases, Dis Colon Rectum, 25, pp. 693-703, (1982)
[7]  
Morson B.C., Volkstat H., Malignant melanoma of the anal canal, Journal of Clinical Pathology, 16, pp. 126-132, (1963)
[8]  
Balch C.M., Soong S.J., Murad T.M., Ingalls A.L., Maddox W.A., A multifactorial analysis of melanoma. II. Prognostic factors in patients with Stage I (localized) melanoma, Surgery, 86, pp. 343-350, (1979)
[9]  
Husa A., Hocherstedt A.K., Anorectal melanoma. A report of 14 cases, Acta Chir Scand, 140, pp. 68-72, (1974)
[10]  
Quan S.H.Q., White J.E., Deddish, Malignant melanoma of the anorectum, Dis Colon Rectum, 2, pp. 275-283, (1959)