POSSIBLE ROLE OF RHODOPSIN IN MAINTAINING BILAYER STRUCTURE IN THE PHOTORECEPTOR MEMBRANE

被引：73

作者：

DEGRIP, WJ ^{[1
]}

DRENTHE, EHS ^{[1
]}

VANECHTELD, CJA ^{[1
]}

DEKRUIJFF, B ^{[1
]}

VERKLEIJ, AJ ^{[1
]}

机构：

[1] STATE UNIV UTRECHT, INST MOLEC BIOL, TRANSISTORIUM 3, NL-3584 CH UTRECHT, NETHERLANDS

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 558卷 / 03期

关键词：

!sup]31[!/sup]P-NMR; Freeze-fracture electron microscopy; Photolysis; Photoreceptor membrane; Rhodopsin;

D O I：

10.1016/0005-2736(79)90269-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

31P-NMR measurements demonstrate that at 37°C, independent of the photolytic state of the photopigment rhodopsin, the lipids in the photoreceptormembrane are almost exclusively organised in a bilayer. In strong contrast, the 31P-NMR spectra of the extracted lipids are characteristic for the hexagonal HII phase and an isotropic phase. The isotropic phase is characterised by freeze-fracture electron microscopy as particles and pits on smooth surfaces, possibly indicating inverted micelles. These results suggest a structural role for rhodopsin in maintaining the photoreceptor membrane lipids in a bilayer configuration. © 1979.

引用

页码：330 / 337

页数：8

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