SYNTHESIS OF A NOVEL ANALOG OF SIALYL-LEWIS-X

被引：34
|
作者：
PRODGER, JC [1 ]
BAMFORD, MJ [1 ]
GORE, PM [1 ]
HOLMES, DS [1 ]
SAEZ, V [1 ]
WARD, P [1 ]
机构：
[1] GLAXO GRP RES LTD,RES & DEV,DEPT MED CHEM 1,GREENFORD UB6 0HE,MIDDX,ENGLAND
来源：
TETRAHEDRON LETTERS | 1995年 / 36卷 / 13期
关键词：
D O I：
10.1016/0040-4039(95)00250-G
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Two different strategies have been developed in order to synthesise an analogue and potential mimic of sialyl Lewis X that incorporates a carboxymethyl group and a C-2-symmetric 2,3-butanediol unit as replacements for the sialic acid and the N-acetylglucosamine residues respectively.
引用
收藏
页码：2339 / 2342
页数：4
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