MULTIPLE MYELOMA REVEALING BY SPHENOID INVOLVEMENT. CASE REPORT

Plasmocytoma rarely involves the skull base. Being solitary or multiple, a progressive course of multiple cranial neuropathies was the most common presentation especially cavernous sinus syndrome. Making diagnosis from the imaging findings was usually difficult. The authors report an 83-old-man with an isolated cavernous sinus syndrome. Neuroradiological investigation revealed destructive lesion of sphenoid, ethmoid, sellar and petroclival areas. A transsphenoidal biopsy showed features of a plamocytoma and a subsequent workup confirmed the presence of multiple myeloma. The neuroimaging features of skull base plasmocytoma are nonspecific. However, this entity should be suggested in the differential diagnosis of invasive sphenoid process.