SYNTHETIC APPROACHES TO ADRIAMYCIN .2. DEGRADATION OF DAUNORUBICIN TO A NON-ASYMMETRIC TETRACYCLIC KETONE AND REFUNCTIONALIZATION OF A-RING TO ADRIAMYCIN

被引：141

作者：

SMITH, TH ^{[1
]}

FUJIWARA, AN ^{[1
]}

LEE, WW ^{[1
]}

WU, HY ^{[1
]}

HENRY, DW ^{[1
]}

机构：

[1] STANFORD RES INST,DEPT BIOORGAN CHEM,MENLO PK,CA 94025

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1977年 / 42卷 / 23期

关键词：

D O I：

10.1021/jo00443a004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：3653 / 3660

页数：8

共 40 条

[1] TOTAL SYNTHESIS OF ANTITUMOR ANTIBIOTIC DAUNORUBICIN - COUPLING OF SUGAR AND AGLYCONE [J].

ACTON, EM ;

FUJIWARA, AN ;

HENRY, DW .

JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (06) :659-660

[2]

ARCAMONE F, 1975, CANCER CHEMOTH REP 3, V6, P123

[3] SYNTHESIS AND ANTITUMOR PROPERTIES OF NEW GLYCOSIDES OF DAUNOMYCINONE AND ADRIAMYCINONE [J].

ARCAMONE, F ;

PENCO, S ;

VIGEVANI, A ;

REDAELLI, S ;

FRANCHI, G ;

DIMARCO, A ;

CASAZZA, AM ;

DASDIA, T ;

FORMELLI, F ;

NECCO, A ;

SORANZO, C .

JOURNAL OF MEDICINAL CHEMISTRY, 1975, 18 (07) :703-707

[4] DAUNOMYCIN .I. STRUCTURE OF DAUNOMYCINONE [J].

ARCAMONE, F ;

BARBIERI, W ;

FRANCESC.G ;

MONDELLI, R ;

OREZZI, P ;

CASSINELLI, G .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (23) :5334-&

[5]

ARCAMONE F, 1969, TETRAHEDRON LETT, P1007

[6]

ARCAMONE F, 1969, CHIM IND-MILAN, V51, P834

[7]

Arcamone F., 1974, [No title captured], Patent No. [US 3803124, 3803124]

[8]

ARCAMONE F, 1976, Patent No. 842930

[9]

BABLER JH, 1974, TETRAHEDRON LETT, P351

[10] ALPHA-METHOXYVINYLLITHIUM AND RELATED METALATED ENOL ETHERS - PRACTICAL REAGENTS FOR NUCLEOPHILIC ACYLATION [J].

BALDWIN, JE ;

HOFLE, GA ;

LEVER, OW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1974, 96 (22) :7125-7127

← 1 2 3 4 →