CHARACTERIZATION OF CDNAS CODING FOR GLUCOSE PHOSPHATE ISOMERASE AND PHOSPHOGLYCERATE KINASE IN CHINESE-HAMSTER OVARY CELL-LINE CHO-K1 AND IDENTIFICATION OF DEFECTS IN R1.1.7, A GLYCOLYSIS-DEFICIENT VARIANT OF CHO-K1

被引：2
|
作者：
HASSANWALKER, AF
MORGAN, MJ
FAIK, P
机构：
[1] Wellcome Laboratory For Molecular Genetics, Division of Biochemistry and Molecular Biology, UMDS, London, SE 1 9RT, Guy's Campus, London Bridge
来源：
SOMATIC CELL AND MOLECULAR GENETICS | 1995年 / 21卷 / 01期
基金：
英国惠康基金;
关键词：
D O I：
10.1007/BF02255824
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Full-length cDNAs for glucose phosphate isomerase (GPI) and phosphoglycerate kinase (PGK) of the Chinese hamster ovary cell line CHO-K1 have been characterized using RT-PCR and cycle sequencing of the PCR-amplified templates. Mutations in both genes have been identified in a glycolysis-deficient Chinese hamster ovary cell line, R1.1.7, derived from CHO-K1 cells.
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页码：75 / 81
页数：7
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