From previous studies, chippers (very light, long-time cigarette smokers) seem not to be nicotine dependent, despite decades of smoking. The effect of tobacco deprivation on chippers' withdrawal reactions was examined. Matched groups of 26 chippers and 25 regular smokers were studied while abstaining or smoking for 2-day blocks, with assessments administered 5 times daily by palm-top computers. As hypothesized, chippers showed no changes as a result of nicotine deprivation. In contrast, regular smokers demonstrated distinct changes in craving, mood, arousal, and sleep disturbance. The computers also tested participants' cognitive performance. Unlike chippers, regular smokers' performance on complex tasks was slower under deprivation; the effect could not be explained by changes in motor performance or simple reaction time. Results suggest performance may have been improved by nicotine rather than worsened by withdrawal.
机构:
Brown Univ, Ctr Alcohol & Addict Studies, 121 South Main St,Box G-S121-4, Providence, RI 02903 USABrown Univ, Ctr Alcohol & Addict Studies, 121 South Main St,Box G-S121-4, Providence, RI 02903 USA
Cassidy, Rachel N.
Colby, Suzanne M.
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Brown Univ, Ctr Alcohol & Addict Studies, 121 South Main St,Box G-S121-4, Providence, RI 02903 USABrown Univ, Ctr Alcohol & Addict Studies, 121 South Main St,Box G-S121-4, Providence, RI 02903 USA
Colby, Suzanne M.
Tidey, Jennifer W.
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Brown Univ, Ctr Alcohol & Addict Studies, 121 South Main St,Box G-S121-4, Providence, RI 02903 USABrown Univ, Ctr Alcohol & Addict Studies, 121 South Main St,Box G-S121-4, Providence, RI 02903 USA
Tidey, Jennifer W.
Jackson, Kristina M.
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Brown Univ, Ctr Alcohol & Addict Studies, 121 South Main St,Box G-S121-4, Providence, RI 02903 USABrown Univ, Ctr Alcohol & Addict Studies, 121 South Main St,Box G-S121-4, Providence, RI 02903 USA
Jackson, Kristina M.
Cioe, Patricia A.
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Brown Univ, Ctr Alcohol & Addict Studies, 121 South Main St,Box G-S121-4, Providence, RI 02903 USABrown Univ, Ctr Alcohol & Addict Studies, 121 South Main St,Box G-S121-4, Providence, RI 02903 USA
Cioe, Patricia A.
Krishnan-Sarin, Suchitra
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机构:
Yale Univ, Tobacco Ctr Regulatory Sci, 34 Pk St, New Haven, CT 06519 USABrown Univ, Ctr Alcohol & Addict Studies, 121 South Main St,Box G-S121-4, Providence, RI 02903 USA
Krishnan-Sarin, Suchitra
Hatsukami, Dorothy
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机构:
Univ Minnesota, Mason Canc Ctr, 425 E River Pkwy, Minneapolis, MN 55455 USABrown Univ, Ctr Alcohol & Addict Studies, 121 South Main St,Box G-S121-4, Providence, RI 02903 USA
机构:
NIDA, Nicotine Psychopharmacol Sect, Clin Pharmacol & Therapeut Branch, Intramural Res Program,NIH,Dept Hlth & Human Serv, Baltimore, MD 21224 USANIDA, Nicotine Psychopharmacol Sect, Clin Pharmacol & Therapeut Branch, Intramural Res Program,NIH,Dept Hlth & Human Serv, Baltimore, MD 21224 USA
Kleykamp, Bethea A.
Jennings, Janine M.
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机构:
Wake Forest Univ, Dept Psychol, Winston Salem, NC 27109 USANIDA, Nicotine Psychopharmacol Sect, Clin Pharmacol & Therapeut Branch, Intramural Res Program,NIH,Dept Hlth & Human Serv, Baltimore, MD 21224 USA
Jennings, Janine M.
Eissenberg, Thomas
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Virginia Commonwealth Univ, Dept Psychol, Richmond, VA 23284 USA
Virginia Commonwealth Univ, Inst Drug & Alcohol Studies, Richmond, VA 23284 USANIDA, Nicotine Psychopharmacol Sect, Clin Pharmacol & Therapeut Branch, Intramural Res Program,NIH,Dept Hlth & Human Serv, Baltimore, MD 21224 USA