UPTAKE MECHANISMS AND INTRACELLULAR TRAFFICKING OF PHOSPHOROTHIOATE MODIFIED OLIGODEOXYNUCLEOTIDES

被引：0
|
作者：
BELTINGER, CP
SMITH, RM
SARGOVI, HU
GEWIRTZ, AM
机构：
[1] CHILDRENS HOSP PHILADELPHIA,DEPT ONCOL,PHILADELPHIA,PA
[2] UNIV PENN,SCH MED,DEPT PATHOL & LAB MED,PHILADELPHIA,PA 19104
[3] UNIV PENN,SCH MED,DEPT INTERNAL MED,PHILADELPHIA,PA 19104
来源：
BLOOD | 1993年 / 82卷 / 10期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：A117 / A117
页数：1
相关论文
共 50 条
  • [21] Amplification of antibody production by phosphorothioate oligodeoxynucleotides
    Branda, RF
    Moore, AL
    Lafayette, AR
    Mathews, L
    Hong, R
    Zon, G
    Brown, T
    McCormack, JJ
    JOURNAL OF LABORATORY AND CLINICAL MEDICINE, 1996, 128 (03): : 329 - 338
  • [22] Multiple mechanisms may contribute to the cellular anti-adhesive effects of phosphorothioate oligodeoxynucleotides
    Khaled, Z
    Benimetskaya, L
    Zeltser, R
    Khan, T
    Sharma, HW
    Narayanan, R
    Stein, CA
    NUCLEIC ACIDS RESEARCH, 1996, 24 (04) : 737 - 745
  • [23] Intra-Endosomal Trafficking Mediated by Lysobisphosphatidic Acid Contributes to Intracellular Release of Phosphorothioate-modified Antisense Oligonucleotides.
    Wang, S.
    Sun, H.
    Liang, X.
    Crooke, S. T.
    MOLECULAR BIOLOGY OF THE CELL, 2017, 28
  • [24] Phosphorothioate-modified oligodeoxynucleotides inhibit human cytomegalovirus replication by blocking virus entry
    Luganini, Anna
    Caposio, Patrizia
    Landolfo, Santo
    Gribaudo, Giorgio
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (03) : 1111 - 1120
  • [25] Modulation of plasma protein binding and in vivo liver cell uptake of phosphorothioate oligodeoxynucleotides by cholesterol conjugation
    Bijsterbosch, MK
    Rump, ET
    De Vrueh, RLA
    Dorland, R
    van Veghel, R
    Tivel, KL
    Biessen, EAL
    van Berkel, TJC
    Manoharan, M
    NUCLEIC ACIDS RESEARCH, 2000, 28 (14) : 2717 - 2725
  • [26] In vivo fate of phosphorothioate antisense oligodeoxynucleotides: Predominant uptake by scavenger receptors on endothelial liver cells
    Bijsterbosch, MK
    Manoharan, M
    Rump, ET
    DeVrueh, RLA
    vanVeghel, R
    Tivel, KL
    Biessen, EAL
    Bennett, CF
    Cook, PD
    vanBerkel, TJC
    NUCLEIC ACIDS RESEARCH, 1997, 25 (16) : 3290 - 3296
  • [27] Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides
    Wang, Shiyu
    Allen, Nickolas
    Vickers, Timothy A.
    Revenko, Alexey S.
    Sun, Hong
    Liang, Xue-hai
    Crooke, Stanley T.
    NUCLEIC ACIDS RESEARCH, 2018, 46 (07) : 3579 - 3594
  • [28] PHOSPHOROTHIOATE OLIGODEOXYNUCLEOTIDES - ANTISENSE OR ANTI-PROTEIN
    KRIEG, AM
    STEIN, CA
    ANTISENSE RESEARCH AND DEVELOPMENT, 1995, 5 (04): : 241 - 241
  • [29] Exploiting the potential of antisense: Beyond phosphorothioate oligodeoxynucleotides
    Stein, CA
    CHEMISTRY & BIOLOGY, 1996, 3 (05): : 319 - 323
  • [30] A systematic exploration of protein uptake and trafficking into intracellular compartments
    Labokha, Aksana
    Minter, Ralph
    PROTEIN SCIENCE, 2015, 24 : 189 - 190
12345