FORMATION OF OXAZOLINES AND THIAZOLINES IN PEPTIDES BY THE MITSUNOBU REACTION

被引：108

作者：

GALEOTTI, N

MONTAGNE, C

PONCET, J

JOUIN, P

机构：

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 20期

关键词：

BETA-HYDROXY ALPHA-AMINO ACIDS; PEPTIDE-MIMICS;

D O I：

10.1016/S0040-4039(00)78864-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Mitsunobu reaction was efficiently used to introduce oxazolines and thiazolines in the peptide backbone. The reaction proceeded from beta-hydroxy alpha-amino acid-containing peptides at room temperature in 58-72% isolated yields.

引用

页码：2807 / 2810

页数：4

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