SYNTHETIC STUDIES ON THE MOLYBDENUM COFACTOR - AN EFFICIENT TOTAL SYNTHESIS OF (+/-)-DEPHOSPHO FORM-A

被引:20
作者
TAYLOR, EC
GOSWAMI, S
机构
[1] Department of Chemistry, Princeton University, Princeton
基金
美国国家卫生研究院;
关键词
D O I
10.1016/0040-4039(91)80106-G
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
(Dephospho) Form A (4b), obtained by oxidative degradation of the molybdenum cofactor, has been efficiently synthesized in racemic form for the first time. This material, as well as its protected derivative 11, are now conveniently available as intermediates for a projected synthesis of the natural cofactor.
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页码:7357 / 7360
页数:4
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