BLOOD-COAGULATION AND SHOCK

被引：17
作者：
SALDEEN, T
机构：
[1] Institute of Forensic Medicine, University of Uppsala, Uppsala
来源：
PATHOLOGY RESEARCH AND PRACTICE | 1979年 / 165卷 / 03期
关键词：
Blood coagulation; Fibrin; Fibrin degradation products; Fibrinolysis inhibition; Increased vascular; Microemboli; permeability; Shock;
D O I：
10.1016/S0344-0338(79)80073-4
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
This report describes how a finding at the autopsy table led to the observation of a clinical syndrome.A synthesis of autopsy experience, clinical investigations, and experimental and biochemical studies were able to shed light on one factor in the pathogenesis of this syndrome, namely blood coagulation with pulmonary microemboli and release and delayed elimination of peptides from fibrin degradation extravascularly in the lungs.These pep tides may both induce increased permeability in the microcirculation and stimulate fibroblast proliferation.Knowledge about the pathogenesis has led to improved prophylaxis and therapy and a reduction of the number of deaths. © 1979, Gustav Fischer Verlag, Stuttgart/New York. All rights reserved.
引用
收藏
页码：221 / 252
页数：32
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