PREPARATION OF 9-CIS-RETINOIC ACID [11,12-H-3(N)] BY PHOTOCHEMICAL ISOMERIZATION

被引：10
|
作者：
DAWSON, MI
HOBBS, PD
CAMERON, JF
RHEE, SW
机构：
[1] Sri International, Menlo Park, California
来源：
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS | 1993年 / 33卷 / 03期
关键词：
9-CIS-RETINOIC ACID [11,12-3H(N); PHOTOLYSIS; ALL-TRANS-RETINOIC ACID [11,12-3H(N);
D O I：
10.1002/jlcr.2580330310
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
All-trans-Retinoic acid [11, 12-H-3(N)] was photochemically isomerized using a fluorescent source to afford a mixture of isomeric retinoic acids, from which 9-cis-retinoic acid[11, 12-H-3(N)] was isolated by reversed-phase HPLC. The identity of 9-cis-retinoic acid [11, 12-H-3(2)] was confirmed by coinjection with the unlabeled acid.
引用
收藏
页码：245 / 247
页数：3
相关论文
共 50 条
  • [1] A PREPARATION OF HIGH SPECIFIC ACTIVITY [11,12-H-3]-9-CIS-RETINOIC ACID
    COE, JW
    HAWES, CR
    TOWERS, P
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 1995, 36 (06): : 587 - 594
  • [2] ISOMERIZATION OF ALL-TRANS-RETINOIC ACID TO 9-CIS-RETINOIC ACID
    URBACH, J
    RANDO, RR
    BIOCHEMICAL JOURNAL, 1994, 299 : 459 - 465
  • [3] CONVENIENT PREPARATION OF 9-CIS-RETINOIC ACID
    COE, JW
    OCONNELL, T
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1994, 4 (02) : 349 - 350
  • [4] 9,13-dicis-retinoic acid as an isomerization product of 9-cis-retinoic acid
    Sass, JO
    Tzimas, G
    Nau, H
    DRUG METABOLISM AND DISPOSITION, 1997, 25 (12) : 1447 - 1448
  • [5] 9,13-dicis-retinoic acid as an isomerization product of 9-cis-retinoic acid - Response
    SolbesMarchetti, MN
    Sampol, E
    Bun, H
    Scoma, H
    Lacarelle, B
    Durand, A
    DRUG METABOLISM AND DISPOSITION, 1997, 25 (12) : 1448 - 1448
  • [6] Nonenzymatic isomerization of 9-cis-retinoic acid catalyzed by sulfhydryl compounds
    Shih, TW
    Lin, TH
    Shealy, YF
    Hill, DL
    DRUG METABOLISM AND DISPOSITION, 1997, 25 (01) : 27 - 32
  • [7] Synthesis of 9-cis-retinoic acid and C-20-[3H3C]-9-cis-retinoic acid with high specific activity
    Tadikonda, Praveen K.
    Lacy, James M.
    Rigdon, Michael G.
    Deluca, Hector F.
    Journal of Labelled Compounds and Radiopharmaceuticals, 1997, 39 (01): : 1 - 10
  • [8] Synthesis of 9-cis-retinoic acid and C-20-[(H3C)-H-3]-9-cis-retinoic acid with high specific activity
    Tadikonda, PK
    Lacy, JM
    Rigdon, MG
    Deluca, HF
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 1997, 39 (01): : 1 - 10
  • [9] THIOL DEPENDENT ISOMERIZATION OF ALL-TRANS-RETINOIC ACID TO 9-CIS-RETINOIC ACID
    URBACH, J
    RANDO, RR
    FEBS LETTERS, 1994, 351 (03) : 429 - 432
  • [10] SYNTHESIS OF HOMOURSODEOXYCHOLIC ACID AND [11,12-H-3 HOMOURSODEOXYCHOLIC ACID
    KURAMOTO, T
    KAWAMOTO, K
    MORIWAKI, S
    HOSHITA, T
    STEROIDS, 1984, 44 (06) : 549 - 559
12345