N-15 NMR-STUDIES OF THE BINDING OF C-15N(-) WITH GOLD(I) DRUGS

被引：10
|
作者：
ISAB, AA
GHAZI, IH
WAZEER, MIM
PERZANOWSKI, HP
机构：
[1] Chemistry Department, King Fahad University of Petroleum and Minerals, Dhahran
来源：
JOURNAL OF INORGANIC BIOCHEMISTRY | 1993年 / 50卷 / 04期
关键词：
D O I：
10.1016/0162-0134(93)80056-F
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
N-15 NMR studies of the interaction of N-15 cyanide ion with gold(I)-thiomalate (Autm) and gold(I)-thioglucose (Autg) have been carried out at pH* 7.40. The chemical shifts of the two N-15 ions containing species (Au(CN)2-)-N-15 and (RS-Au-CN-)-N-15 (where RS- = tm- or tg-)were identified at 265.94 and 260.30 ppm, respectively. From the broadened N-15 NMR signals, approximate life times of the RS-Au-CN- species were calculated.
引用
收藏
页码：299 / 304
页数：6
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