未找到相关数据
ACTION OF 5-FLUOROURACIL ON RATS WITH DMH-INDUCED COLON CANCER
被引：0
作者：
FERRE, J
CUERVASMONS, M
MORTE, L
MARTINEZ, A
CAJAL, SRY
机构：
关键词：
5-FLUOROURACIL;
DMH;
COLON CANCER;
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
An experimental model to observe the action of 5-fluorouracil on rats with DMH-induced cancer of colon was designed. Ten Wistar rats were injected weekly with 25 subcutaneous doses (21 mg/kg) of DMH, and another ten, coinciding with the last 10 doses of the former, received intraperitoneally 10 mg/kg of the cytostatic agent. The animals were sacrificed 7 days after the last injection and samples of the colon processed by the <<swiss roll>> technique. Differences in the weight of the animals and in the localization, size and macro and microscopic type of the tumours encountered, as well as the localization and grade of the dysplasias are studied.
引用
收藏
页码：23 / 28
页数：6
相关论文