Dataset for the role of sustained attention in memory formation of transgenic mice for Alzheimer's disease

被引：0

作者：

Schowe, Natalia Mendes ^{[1
]}

de Oliveira, Eduardo Moreira ^{[2
]}

Buck, Hudson Sousa ^{[3
]}

Viel, Tania Araujo ^{[1
,4
]}

机构：

[1] Univ Sao Paulo, Inst Biomed Sci, Grad Course Pharmacol, Sao Paulo, Brazil

[2] Univ Sao Paulo, Sch Med, Dept Cognit Neurol, Grad Course Neurol, Sao Paulo, Brazil

[3] Santa Casa Sao Paulo Sch Med Sci, Dept Physiol Sci, Sao Paulo, Brazil

[4] Univ Sao Paulo, Sch Arts Sci & Humanities, Sao Paulo, Brazil

来源：

DATA IN BRIEF | 2016年 / 6卷

基金：

巴西圣保罗研究基金会;

关键词：

Sustained attention; Memory; Alzheimer's disease; Nicotinic; Receptor; Hippocampus;

D O I：

10.1016/j.dib.2016.01.015

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Weekly submission of rats to active avoidance apparatus can be considered a neurostimulation strategy, once it can improve memory and can increase the density of receptors from different neurotransmitter systems in brain areas related to memory. These benefits were observed in rats chronically infused with amyloid-beta peptide. In the present work it is presented that the same benefit for memory was observed in five months old transgenic mice for Alzheimers disease (TG-PDGFB-APP(Sw,Ind)). However, at this age, no change in density of nicotinic receptors was observed. (C) 2016 The Authors. Published by Elsevier Inc. This is an open access article under the CCBY license.

引用

页码：763 / 768

页数：6

共 5 条

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