DISSEMINATION OF AMIKACIN RESISTANCE GENE APHA6 IN ACINETOBACTER SPP

被引：45

作者：

LAMBERT, T

GERBAUD, G

BOUVET, P

VIEU, JF

COURVALIN, P

机构：

[1] INST PASTEUR, INSERM, U199, UNITE ENTEROBACTERIES, F-75724 PARIS 15, FRANCE

[2] CTR ETUDE PHARMACEUT, F-92296 CHATENAY MALABRY, FRANCE

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1990年 / 34卷 / 06期

关键词：

D O I：

10.1128/AAC.34.6.1244

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The distribution of the aphA6 gene, encoding a 3'-aminoglycoside phosphatotransferase type VI, was studied by dot blot hybridization with 115 amikacin-resistaznt Acetinobacter strains from various geographical areas. Nucleotide sequences related to aphA6 were found in 109 strains belonging to seven species. As inferred from results of Southern hybridization, dissemination of amikacin resistance in Acetinobacter spp. is due to a gene rather than a strain of plasmid epidemic.

引用

页码：1244 / 1248

页数：5

共 26 条

[1]

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