REPRODUCIBILITY OF HISTOLOGIC CLASSIFICATION OF GASTRIC-CANCER

被引：48

作者：

PALLI, D

BIANCHI, S

CIPRIANI, F

DUCA, P

AMOROSI, A

AVELLINI, C

RUSSO, A

SARAGONI, A

TODDE, P

VALDES, E

VINDIGNI, C

BLOT, WJ

FRAUMENI, JF

BUIATTI, E

机构：

[1] CTR STUDIO & PREVENZ ONCOL,EPIDEMIOL UNIT,VIALE VOLTA 171,I-50131 FLORENCE,ITALY

[2] UNIV FLORENCE,POLICLIN CAREGGI,IST ANAT PATOL,I-50134 FLORENCE,ITALY

[3] UNIV SIENA,IST ANAT PATOL,I-53100 SIENA,ITALY

[4] UNIV MILAN,IST BIOMETRIA & STAT,I-20133 MILAN,ITALY

[5] OSPED IMOLA,SERV ANAT PATOL,I-40026 IMOLA,ITALY

[6] OSPED MORGAGNI PIERANTONI,SERV ANAT PATOL,I-47010 FORLI,ITALY

[7] OSPED BROTZU,SERV ANAT PATOL,I-09100 CAGLIARI,ITALY

[8] OSPED SS TRINITA,SERV ANAT PATOL,I-09100 CAGLIARI,ITALY

[9] NCI,BETHESDA,MD 20892

来源：

BRITISH JOURNAL OF CANCER | 1991年 / 63卷 / 05期

关键词：

D O I：

10.1038/bjc.1991.171

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A panel review of histologic specimens was carried out as part of a multi-centre case-control study of gastric cancer (GC) and diet. Comparisons of diagnoses of 100 GCs by six pathologists revealed agreement in histologic classification for about 70-80% of the cancers. Concordance was somewhat higher when using the Lauren rather than the Ming or World Health Organization classification systems. Histologic types from reading biopsy tissue agreed with those derived from surgical specimens for 65-75% of the 100 tumours. Intra-observer agreement in histologic classification, assessed by repeat readings up to 3 years apart by one pathologist, was 95%. The findings indicate that, although overall concordance was good, it is important to standardise diagnoses in multi-centre epidemiologic studies of GC by histologic type.

引用

页码：765 / 768

页数：4

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