FAILURE TO DETECT CIRCULATING IMMUNE-COMPLEXES IN ALLERGIC PATIENTS ON INJECTION THERAPY

被引：15

作者：

KEMLER, BJ

FRANKLIN, WD

ALPERT, E

BLOCH, KJ

机构：

[1] MASSACHUSETTS GEN HOSP,MED SERV,ALLERGY UNIT,BOSTON,MA 02114

[2] MASSACHUSETTS GEN HOSP,MED SERV,CLIN IMMUNOL UNIT,BOSTON,MA 02114

[3] HARVARD UNIV,SCH MED,DEPT MED,BOSTON,MA 02115

来源：

CLINICAL ALLERGY | 1979年 / 9卷 / 05期

关键词：

D O I：

10.1111/j.1365-2222.1979.tb02511.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Injection therapy for allergic diseases may create an environment conducive to circulating immune complex formation. Therefore, we examined the sera of eleven patients receiving injection therapy for the presence of circulating immune complexes. A sensitive Raji cell radioimmune assay was used to examine the sera prior to and 4, 8 and 24 hours after allergenic injection. Levels measured in these sera were compared to values obtained from forty‐two healthy controls. Ten of eleven allergic patients receiving injection therapy had values within the normal range prior to maintenance injection. These ten patients also had normal values for circulating immune complexes at each interval after maintenance injection. The data suggest that circulating immune complexes are not a routine consequence of injection therapy for allergic disease. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：473 / 478

页数：6

共 13 条

[1] CIRCULATING IMMUNE-COMPLEXES IN PATIENTS WITH ATOPIC ALLERGY [J].