BIOASSAY QUANTITATION OF RAMOPLANIN IN HUMAN AND IN NONPRIMATE SERA

被引：2
作者：
KENNY, MT
BRACKMAN, MA
DULWORTH, JK
机构：
[1] Microbiology Department, Marion Merrell Dow Inc., Kansas City, MO
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 1994年 / 18卷 / 02期
关键词：
D O I：
10.1016/0732-8893(94)90076-0
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
This study developed and validated a bioassay for ramoplanin in human, dog, rabbit, and rat sera. Mean analyte recoveries and coefficients of variation for duplicate assays with each serum using coded and spiked (30-720 ng/ml) samples ranged from 93.5% to 106.3% and from 1.8% to 5.4% respectively. All correlation coefficients were > 0.99 and, for each serum, there was no significant difference in overall analyte recovery between the 2 test days.
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页码：117 / 119
页数：3
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