LIPID-PEROXIDATION AND PROTECTIVE ENZYMES DURING MYOCARDIAL-INFARCTION

被引：74

作者：

LOEPER, J ^{[1
]}

GOY, J ^{[1
]}

ROZENSZTAJN, L ^{[1
]}

BEDU, O ^{[1
]}

MOISSON, P ^{[1
]}

机构：

[1] CHU ST ANTOINE,MED EXPTL LAB,F-75571 PARIS 12,FRANCE

来源：

CLINICA CHIMICA ACTA | 1991年 / 196卷 / 2-3期

关键词：

MYOCARDIAL INFARCTION; LIPID PEROXIDE; MALONDIALDEHYDE; DETOXIFICATION ENZYMES;

D O I：

10.1016/0009-8981(91)90064-J

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Fasting blood taken from 34 patients with myocardial infarction, 19 with unstable angina and 40 healthy controls, was analysed for malondialdehyde and erythrocyte detoxification enzymes, superoxide dismutase and glutathione peroxidase. Malondialdehyde concentration was raised in the patients with myocardial infarction during the initial 48 h after an attack, and correlated with the severity of the attack. 12 days after the infarct, malondialdehyde concentrations were lower but still raised. superoxide dismutase activity was below normal during the initial 48 h post infarct and raised twelve days after. Glutathione peroxidase was reduced after 12 days. Similar, but less marked changes were seen in the patients unstable angina.

引用

页码：119 / 125

页数：7

共 23 条

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