EFFECT OF BETA-AGONISTS ON PROTEIN-TURNOVER IN ADIPOSE-TISSUE

被引：0
|
作者：
ROGERS, KL
FAGAN, JM
机构：
[1] Department of Animal Sciences, Rutgers University, New Brunswick
来源：
LIFE SCIENCES | 1991年 / 48卷 / 02期
关键词：
D O I：
10.1016/0024-3205(91)90407-3
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Chronic administration (21 days) of the beta agonist cimaterol to rats decreased epididymal fat by 27%, and inhibited in vitro rates of protein synthesis by 34% and net protein breakdown by 71% in adipose tissue. Likewise, incubation of rat adipose tissue with cimaterol and isoproterenol stimulated lipolysis, and inhibited protein synthesis and degradation. Thus, in addition to affecting muscle mass and lipid metabolism, beta agonists appear to slow rates of protein turnover in adipose tissue. © 1991.
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页码：143 / 148
页数：6
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