MUTAGENIC EFFECTS OF OZONE ON HUMAN-CELLS EXPOSED INVIVO AND INVITRO BASED ON SISTER CHROMATID EXCHANGE ANALYSIS

被引：43
作者：
GUERRERO, RR
ROUNDS, DE
OLSON, RS
HACKNEY, JD
机构：
[1] Pasadena Foundation for Medical Research, Pasadena
来源：
ENVIRONMENTAL RESEARCH | 1979年 / 18卷 / 02期
关键词：
D O I：
10.1016/0013-9351(79)90110-5
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
A sister chromatid exchange (SCE) analysis was performed on circulating lymphocytes collected from young human volunteers exposed to 0.5 ppm ozone for 2 h, an exposure simulating conditions in severe air pollution episodes. SCE analysis was also performed on diploid human fetal lung cells (WI-38) exposed to 0, 0.25, 0.50, 0.75 and 1.00 ppm ozone for 1 h in vitro. No increase in SCE over controls was demonstrated in the lymphocyte chromosomes. A clear dose-related increase in SCE was observed in the WI-38 cells exposed in vitro.
引用
收藏
页码：336 / 346
页数：11
相关论文
共 50 条
[41]   TRIETHYLENE MELAMINE-INDUCED SISTER-CHROMATID EXCHANGE IN MURINE LYMPHOCYTES EXPOSED INVIVO [J].
NEFT, RE ;
SCHOL, HM ;
CASCIANO, DA .
MUTATION RESEARCH, 1989, 222 (04) :323-328
[42]   SISTER CHROMATID EXCHANGES AND INHIBITION OF DNA-SYNTHESIS IN IRRADIATED HUMAN-CELLS [J].
PLESKACH, NM ;
ANDRIADZE, MI ;
MIKHELSON, VM ;
ZHESTYANIKOV, VD .
ACTA BIOLOGICA HUNGARICA, 1990, 41 (1-3) :209-213
[43]   SISTER-CHROMATID EXCHANGE INDUCTION PRODUCED BY INVIVO AND INVITRO EXPOSURE TO ALPHA-ASARONE [J].
MORALESRAMIREZ, P ;
MADRIGALBUJAIDAR, E ;
MERCADERMARTINEZ, J ;
CASSANI, M ;
GONZALEZ, G ;
CHAMORROCEVALLOS, G ;
SALAZARJACOBO, M .
MUTATION RESEARCH, 1992, 279 (04) :269-273
[44]   EFFECT OF TETRANDRINE ON MICRONUCLEUS FORMATION AND SISTER-CHROMATID EXCHANGE IN BOTH INVITRO AND INVIVO ASSAYS [J].
XING, SG ;
SHI, XC ;
WU, ZL ;
WHONG, WZ ;
ONG, T .
MUTATION RESEARCH, 1989, 224 (01) :5-10
[45]   DEPENDENCE OF SISTER CHROMATID EXCHANGES ON DURATION OF EXPOSURE OF HUMAN-CELLS TO ETHYLENIMINE DERIVATIVES [J].
LISTOPAD, GG ;
CHEBOTAREV, AN .
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 1981, 92 (07) :938-940
[46]   PREDICTION OF INVIVO TUMOR RESPONSE TO CHEMOTHERAPEUTIC-AGENTS BY THE INVITRO SISTER CHROMATID EXCHANGE ASSAY [J].
TOFILON, PJ ;
BASIC, I ;
MILAS, L .
CANCER RESEARCH, 1985, 45 (05) :2025-2030
[47]   INUTERO ANALYSIS OF SISTER CHROMATID EXCHANGE - DIFFERENTIAL SENSITIVITY OF FETAL TISSUES TO MUTAGENIC DAMAGE [J].
KRAM, D ;
BYNUM, G ;
SENULA, G ;
BICKINGS, C ;
SCHNEIDER, E .
ENVIRONMENTAL MUTAGENESIS, 1980, 2 (02) :246-246
[48]   EFFECTS OF BENZENE ON SISTER CHROMATID EXCHANGE IN HUMAN-LYMPHOCYTES [J].
DIAZ, M ;
FIJTMAN, N ;
CARRICARTE, V ;
BRAIER, L ;
DIEZ, J .
ENVIRONMENTAL MUTAGENESIS, 1979, 1 (02) :177-177
[49]   SISTER CHROMATID EXCHANGE INDUCTION IN HUMAN-LYMPHOCYTES BY INVITRO EXPOSURE TO CCNU [J].
MCKENZIE, WH ;
LAMBERT, B .
AMERICAN JOURNAL OF HUMAN GENETICS, 1981, 33 (06) :A147-A147
[50]   Sister chromatid exchange in human lymphocytes exposed to isoflurane and nitrous oxide in vitro [J].
Hoerauf, KH ;
Schrögendorfer, KF ;
Wiesner, G ;
Gruber, M ;
Spacek, A ;
Kress, HG ;
Rüdiger, HW .
BRITISH JOURNAL OF ANAESTHESIA, 1999, 82 (02) :268-270
12345