STUDIES ON MITOMYCINS .3. SYNTHESIS AND PROPERTIES OF MITOMYCIN DERIVATIVES

被引:46
作者
MATSUI, M
YAMADA, Y
UZU, K
HIRATA, T
机构
[1] Department of Agricultural Chemistry, University of Tokyo
关键词
D O I
10.7164/antibiotics.21.189
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
About sixty derivatives of mitomycin were synthesized from natural mito-mycins and subjected to antibacterial and antitumor tests. Some of them were more effective than mitomycin C. The structure-activity relationship of derivatives were also investigated. © 1968, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
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页码:189 / &
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