VIMENTIN IN ORAL SQUAMOUS-CELL CARCINOMA

被引：27
|
作者：
DEARAUJO, VC [1 ]
PINTO, DS [1 ]
DESOUSA, SOM [1 ]
NUNES, FD [1 ]
DEARAUJO, NS [1 ]
机构：
[1] UNIV SAO PAULO,SCH DENT,DEPT ORAL PATHOL,SAO PAULO,BRAZIL
来源：
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY | 1993年 / 250卷 / 02期
关键词：
VIMENTIN; ORAL SQUAMOUS CELL CARCINOMA; HISTOLOGICAL GRADING;
D O I：
10.1007/BF00179308
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
The relationship between the histological grading of malignancy and the expression of vimentin and cytokeratin was studied in 43 cases of oral squamous cell carcinoma. Immunohistochemical analysis was carried out with the avidin-biotin method using monoclonal antibody anti-vimentin, and the peroxidase anti-peroxidase method using the polyclonal antibody anti-cytokeratin. All cases were classified according to the histological malignancy grading system proposed by Anneroth. All of the carcinomas were found to express cytokeratin, while 60.4% expressed vimentin. Vimentin was particularly noted in all tumors scored to have highly malignant cells.
引用
收藏
页码：105 / 109
页数：5
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