IMPAIRED GROWTH IN CHILDREN WITH ASTHMA DURING TREATMENT WITH CONVENTIONAL DOSES OF INHALED CORTICOSTEROIDS

被引：37

作者：

THOMAS, BC ^{[1
]}

STANHOPE, R ^{[1
]}

GRANT, DB ^{[1
]}

机构：

[1] INST CHILD HLTH,MED UNIT,LONDON WC1N 1EH,ENGLAND

来源：

ACTA PAEDIATRICA | 1994年 / 83卷 / 02期

关键词：

ASTHMA; GROWTH SUPPRESSION; INHALED CORTICOSTEROIDS;

D O I：

10.1111/j.1651-2227.1994.tb13050.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We describe 6 (4F, 2M) prepubertal children with moderate asthma diagnosed at a mean age of 2.8 years. All patients were treated with inhaled corticosteroids in a dose of between 300 and 800 mcg of beclomethasone diproprionate (becotide) daily, given either as an aerosol or rotahaler. Mean height velocity SDS decreased from -0.8 (range +0.5 to -2.0) to -3.2 (range -1.3 to -4.8) when the dose was increased. Alternatively, when the dose was reduced or stopped, mean height velocity SDS increased from -3.2 (range -2.0 to -4.8) to +0.8 (range -1.2 to +2.7). Careful assessment of height velocity is indicated in all children receiving treatment with inhaled corticosteroids.

引用

页码：196 / 199

页数：4

共 11 条

[1] TREATMENT OF CHILDHOOD ASTHMA FOR 13 MONTHS AND LONGER WITH BECLOMETHASONE DIPROPIONATE AEROSOL [J].