CHRONIC ULCERATIVE STOMATITIS ASSOCIATED WITH A SPECIFIC IMMUNOLOGICAL MARKER

被引：59

作者：

JAREMKO, WM

BEUTNER, EH

KUMAR, V

KIPPING, H

CONDRY, P

ZEID, MY

KAUFFMAN, CL

TATAKIS, DN

CHORZELSKI, TP

机构：

[1] SUNY BUFFALO, DEPT MICROBIOL, 219 SHERMAN HALL, BUFFALO, NY 14260 USA

[2] SUNY BUFFALO, DEPT DERMATOL, BUFFALO, NY 14260 USA

[3] WILFORD HALL USAF MED CTR, DEPT DERMATOL, LACKLAND AFB, TX 78236 USA

[4] UNIV ROCHESTER, DEPT DERMATOL, ROCHESTER, NY 14627 USA

[5] BUFFALO GEN HOSP, DEPT PATHOL, BUFFALO, NY 14203 USA

[6] WASHINGTON HOSP CTR, DEPT DERMATOL, WASHINGTON, DC 20010 USA

[7] SUNY BUFFALO, DEPT ORAL BIOL, BUFFALO, NY 14260 USA

[8] MED ACAD WARSAW, DEPT DERMATOL, PL-02032 WARSAW, POLAND

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 1990年 / 22卷 / 02期

关键词：

D O I：

10.1016/0190-9622(90)70027-F

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Four elderly women with chronic oral ulcerations are described. The lesions are chronic, erosive, or ulcerative; occur on the gingival, buccal, or lingual mucosa; and may occur in the form of desquamative gingivitis. The histopathologic findings are nondiagnostic. The disease is refractory to local and systemic corticosteroids, but treatment with hydroxychloroquine may be effective. Both in vivo binding to the oral mucosa and skin of a stratified epithelium-specific antinuclear antibody and high titers of these antibodies in serum are markers of this disease, which we refer to as chronic ulcerative stomatitis associated with stratified epitheliumspecific antinuclear antibody. © 1990, American Academy of Dermatology, Inc.. All rights reserved.

引用

页码：215 / 220

页数：6

共 16 条

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[2]

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[3]

Beutner EH, 1987, IMMUNOPATHOLOGY SKIN, P3

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