Distinct requirement of RNA polymerase II CTD phosphorylations in budding and fission yeast

被引:19
|
作者
Cassart, Clement [1 ]
Drogat, Julie [1 ]
Migeot, Valerie [1 ]
Hermand, Damien [1 ]
机构
[1] Univ Namur, Namur Res Coll NARC, Namur, Belgium
来源
TRANSCRIPTION-AUSTIN | 2012年 / 3卷 / 05期
关键词
RNA polymerase II; CTD; phosphorylation; cell differentiation;
D O I
10.4161/trns.21066
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The "CTD code" links the combinatorial potential of the modifications found on the Rpb1 C-terminal domain (CTD) to the growing group of CTD binding effectors. The genetic dissection of serine 2 and serine 7 function within the CTD in both budding and fission yeast reveals distinct in vivo requirement.
引用
收藏
页码:231 / 234
页数:4
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