LONG-TERM EFFECTS OF RITODRINE ON BLOOD-PRESSURE AND HEART-RATE OF ADOLESCENTS EXPOSED DURING THE PRENATAL STAGE

被引：9

作者：

ALVAREZ, M

PITA, S

COSTAS, E

CUPEIRO, A

CHAVES, OF

GARCIA, M

SOLA, A

GOYANES, V

机构：

[1] CTR SAUDE CAMBRE,LA CORUNA,SPAIN

[2] UNIV COMPLUTENSE MADRID,FAC VET,DEPT PROD ANIM GENET,MADRID,SPAIN

[3] COMPLEJO HOSP JUAN CANALEJO,SECC GENET,LA CORUNA,SPAIN

来源：

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1995年 / 59卷 / 02期

关键词：

CARDIOVASCULAR EFFECTS; RITODRINE; PRENATAL STAGE;

D O I：

10.1016/0028-2243(95)02045-T

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: To determine the long term cardiovascular effects in adolescents exposed to ritodrine during prenatal stage. Study design: Twenty-seven ritodrine-exposed subjects and 19 controls, of both sexes, clinically healthy, and born at normal term, were evaluated for systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) each during 48 hours, with a Colin Ambulatory monitor. Data analysis were performed by individual Cosinor method, and non-parametric Mann Whitney's test and Lamotte procedures. Results: Adolescents who were exposed to ritodrine showed losses in the HR rhythm and rising middle pulse values. Although SBP and DBP rhythm remains constant, the increase of maximum and minimum values for SBP as well as a rise of maximal rates of DBP suggest a possible hypertensive effect mediated by beta mimetic exposure. Conclusion: This study suggests a hypertensive effect mediated by beta mimetic exposure.

引用

页码：137 / 141

页数：5

共 20 条

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