PREVALENCE AND PREDICTORS OF METABOLIC SYNDROME IN PATIENTS WITH CORONARY ARTERY DISEASE

Objective: To identify the prevalence and predictors of metabolic syndrome using NCEP ATP III guidelines in patients with CAD who underwent angiography at Karachi Institute of Heart Disease (KIHD). Methodology: This cross-sectional study was conducted at the Department of Cardiology; Karachi Institute of Heart Disease from 1st March to 31st December 2016. Patients with confirmed diagnosis of CAD after satisfying the inclusion and exclusion criteria were recruited in this study through non-probability consecutive sampling technique. Data was collected on demographics (i.e. age, gender, and ethnicity) and co-morbidities (i.e. diabetes and hypertension). Metabolic syndrome in patients with CAD was assessed according to the 2011 NCEP ATP III guidelines. Moreover, severity of CAD in patients was also recorded as well as systolic and diastolic blood pressure and biochemical parameters. The data was analysed using SPSS version 21. Results: Among 400 participants, majority (60%) of the participants with CAD were diagnosed with metabolic syndrome. Significantly greater proportion of females (51.2% vs. 21.9%; p = 0.001) were diagnosed with metabolic syndrome. The mean weight, height, BMI and waist circumference was significantly higher in CAD patients diagnosed with metabolic syndrome. Significant difference was not observed in severity of CAD between patients with and without metabolic syndrome. Conclusion: The study highlighted a higher prevalence of metabolic syndrome evaluated using the 2011 NCEP ATP III guidelines among patients with CAD.