INITIAL CHANGES IN DEOXYRIBONUCLEOPROTEIN COMPLEXES OF KANGAROO LYMPHOCYTES STIMULATED WITH PHYTOHAEMAGGLUTININ

被引：21

作者：

BURTON, DW

机构：

[1] Zoology Department, Victoria University of Wellington

来源：

EXPERIMENTAL CELL RESEARCH | 1968年 / 49卷 / 02期

关键词：

D O I：

10.1016/0014-4827(68)90181-X

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Early changes induced in kangaroo lymphocytes by PHA have been studied by alkaline fast green microspectrophotometry and dry mass measurement. In lymphocytes exposed to PHA, there is a 20-25 per cent decrease in stainability with alkaline fast green, an initial decrease in nuclear dry mass, and an increase in cytoplasmic dry mass. These findings support the hypothesis that PHA induces blastogenesis in lymphocytes through the removal of histone from the DNP complex. © 1968.

引用

收藏

页码：300 / &

相关论文

共 15 条

[1] A SELECTIVE STAINING METHOD FOR THE BASIC PROTEINS OF CELL NUCLEI [J].

ALFERT, M ;

GESCHWIND, II .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1953, 39 (10) :991-999

[2] ACETYLATION + METHYLATION OF HISTONES + THEIR POSSIBLE ROLE IN REGULATION OF RNA SYNTHESIS [J].

ALLFREY, VG ;

FAULKNER, R ;

MIRSKY, AE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1964, 51 (05) :786-+

[3] EFFECT OF PHYTOHAEMAGGLUTININ ON HUMAN SERUM AND CELL PROTEINS [J].

BECKMAN, L .

NATURE, 1962, 195 (4841) :582-&

[4] ANTIGEN-INDUCED CHANGES IN LYMPHOID CELL HISTONES .I. THYMUS [J].

BLACK, MM ;

ANSLEY, HR .

JOURNAL OF CELL BIOLOGY, 1965, 26 (01) :201-&

[5] RNA METABOLISM IN LYMPHOCYTES STIMULATED BY PHYTOHEMAGGLUTININ - INITIAL RESPONSES TO PHYTOHEMAGGLUTININ [J].

COOPER, HL ;

RUBIN, AD .

BLOOD-THE JOURNAL OF HEMATOLOGY, 1965, 25 (06) :1014-&

[6] SYNTHESIS OF NONRIBOSOMAL RNA BY LYMPHOCYTES - A RESPONSE TO PHYTOHEMAGGLUTININ TREATMENT [J].

COOPER, HL ;

RUBIN, AD .

SCIENCE, 1966, 152 (3721) :516-&

[7] CULTURE OF HUMAN WHITE CELLS USING DIFFERENTIAL LEUCOCYTE SEPARATION [J].

HASTINGS, J ;

HIRSCHHORN, K ;

FREEDMAN, S ;

COOPER, HL ;

RENDON, O .

NATURE, 1961, 192 (480) :1214-&

[8]

HIRSCHHORN K, 1963, LANCET, V2, P305

[9] HISTONE, A SUPPRESSOR OF CHROMOSOMAL RNA SYNTHESIS [J].

HUANG, RC ;

BONNER, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1962, 48 (07) :1216-&

[10] INITIAL CHANGES OF DEOXYRIBONUCLEOPROTEIN AND SYNTHESIS OF NUCLEIC ACID IN PHYTOHEMAGGLUTININE-STIMULATED HUMAN LEUCOCYTES IN VITRO [J].

KILLANDE.D ;

RIGLER, R .

EXPERIMENTAL CELL RESEARCH, 1965, 39 (2-3) :701-&