EFFECT OF HORMONE REPLACEMENT THERAPY AND CALCITONIN ON BONE MASS IN POSTMENOPAUSAL WOMEN

被引：15
作者：
MESCHIA, M [1 ]
BRINCAT, M [1 ]
BARBACINI, P [1 ]
MAINI, MC [1 ]
MARRI, R [1 ]
CROSIGNANI, PG [1 ]
机构：
[1] UNIV MALTA,SCH MED,MSIDA,MALTA
来源：
EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1992年 / 47卷 / 01期
关键词：
HRT; CALCITONIN; BONE LOSS;
D O I：
10.1016/0028-2243(92)90214-J
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
A total of 104 postmenopausal women were randomly assigned to different therapeutic regimens: (a) calcitonin, (b) estrogen/progestogen (HRT) plus calcitonin, (c) estrogen/progestogen (HRT), (d) and the control group. The bone mass of the lumbar vertebrae of all patients was assessed with a dual beam photon absorptiometer (Norland GD 153). The 73 patients who completed the 1-yr study showed that postmenopausal bone loss could be prevented by either estrogen/progestogen (HRT) or calcitonin. In addition, the combination of hormonel replacement therapy and calcitonin not only prevented postmenopausal bone loss but resulted in a significant 10% gain in bone mass (P < 0.001).
引用
收藏
页码：53 / 57
页数：5
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