EFFECT OF HORMONE REPLACEMENT THERAPY AND CALCITONIN ON BONE MASS IN POSTMENOPAUSAL WOMEN

被引：15

作者：

MESCHIA, M ^{[1
]}

BRINCAT, M ^{[1
]}

BARBACINI, P ^{[1
]}

MAINI, MC ^{[1
]}

MARRI, R ^{[1
]}

CROSIGNANI, PG ^{[1
]}

机构：

[1] UNIV MALTA,SCH MED,MSIDA,MALTA

来源：

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY | 1992年 / 47卷 / 01期

关键词：

HRT; CALCITONIN; BONE LOSS;

D O I：

10.1016/0028-2243(92)90214-J

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

A total of 104 postmenopausal women were randomly assigned to different therapeutic regimens: (a) calcitonin, (b) estrogen/progestogen (HRT) plus calcitonin, (c) estrogen/progestogen (HRT), (d) and the control group. The bone mass of the lumbar vertebrae of all patients was assessed with a dual beam photon absorptiometer (Norland GD 153). The 73 patients who completed the 1-yr study showed that postmenopausal bone loss could be prevented by either estrogen/progestogen (HRT) or calcitonin. In addition, the combination of hormonel replacement therapy and calcitonin not only prevented postmenopausal bone loss but resulted in a significant 10% gain in bone mass (P < 0.001).

引用

页码：53 / 57

页数：5

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