A CONSERVED CLEAVAGE-SITE MOTIF IN CHLOROPLAST TRANSIT PEPTIDES

被引：339
作者：
GAVEL, Y
VONHEIJNE, G
机构：
[1] KAROLINSKA INST, CTR BIOTECHNOL, NOVUM, DEPT MOLEC BIOL, S-14152 HUDDINGE, SWEDEN
[2] ROYAL INST TECHNOL, DEPT THEORET PHYS, THEORET BIOPHYS RES GRP, S-10044 STOCKHOLM 70, SWEDEN
来源：
FEBS LETTERS | 1990年 / 261卷 / 02期
关键词：
Chloroplast; Protein import; Protein targeting; Stromal protease; Transit peptide;
D O I：
10.1016/0014-5793(90)80614-O
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A collection of 32 stroma-targeting chloroplast transit peptides with known cleavage sites have been analysed in terms of amino acid preferences in the vicinity of the processing site. A loosely conserved consensus motif (Val/Ile)-X-(Ala/Cys)↓Ala is found in the majority of the transit peptides. About 30% of the sequences have a perfect match to the consensus. When such a match is found, there is a 90% probability that it specifies the correct cleavage site. © 1990.
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页码：455 / 458
页数：4
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