EFFECT OF INSULIN ON GLUCOSE-6-PHOSPHATE-DEHYDROGENASE AND FATTY-ACID SYNTHETASE-ACTIVITY IN MOUSE-LIVER

被引：4

作者：

KUKULANSKY, T ^{[1
]}

YAGIL, G ^{[1
]}

机构：

[1] WEIZMANN INST SCI,DEPT CELL BIOL,REHOVOT,ISRAEL

来源：

HORMONE AND METABOLIC RESEARCH | 1979年 / 11卷 / 01期

关键词：

D O I：

10.1055/s-0028-1092673

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Regulation of glucose 6-phosphate dehydrogenase and fatty acid synthetase activity in mouse liver is examined in diabetic and normal mice. Up to a 4-fold increase of both enzymes can be observed in streptozotocin diabetic mice when transferred to a fatless, inducing diet. Administration of insulin does not increase enzyme activity at several doses and under a variety of conditions. This is a strong indication that insulin is not a necessary component of the induction system.

引用

页码：14 / 19

页数：6

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