EFFECT OF INSULIN ON GLUCOSE-6-PHOSPHATE-DEHYDROGENASE AND FATTY-ACID SYNTHETASE-ACTIVITY IN MOUSE-LIVER

被引：4
|
作者：
KUKULANSKY, T [1 ]
YAGIL, G [1 ]
机构：
[1] WEIZMANN INST SCI,DEPT CELL BIOL,REHOVOT,ISRAEL
来源：
HORMONE AND METABOLIC RESEARCH | 1979年 / 11卷 / 01期
关键词：
D O I：
10.1055/s-0028-1092673
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Regulation of glucose 6-phosphate dehydrogenase and fatty acid synthetase activity in mouse liver is examined in diabetic and normal mice. Up to a 4-fold increase of both enzymes can be observed in streptozotocin diabetic mice when transferred to a fatless, inducing diet. Administration of insulin does not increase enzyme activity at several doses and under a variety of conditions. This is a strong indication that insulin is not a necessary component of the induction system.
引用
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页码：14 / 19
页数：6
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