DIFFERENTIAL METABOLISM OF THE ENANTIOMERS OF PRIMAQUINE

被引：22

作者：

BAKER, JK ^{[1
]}

MCCHESNEY, JD ^{[1
]}

机构：

[1] UNIV MISSISSIPPI,SCH PHARM,PHARMACEUT SCI RES INST,UNIVERSITY,MS 38677

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1988年 / 77卷 / 05期

关键词：

D O I：

10.1002/jps.2600770503

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：380 / 382

页数：3

共 8 条

[1] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC ANALYSIS OF THE METABOLISM OF PRIMAQUINE AND THE IDENTIFICATION OF A NEW MAMMALIAN METABOLITE [J].

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[2] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION OF THE ENANTIOMERS AND DIASTEREOMERS OF PRIMAQUINE AND ITS METABOLITES [J].

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CLARK, AM ;

HUFFORD, CD .

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[3] METABOLISM AND DISTRIBUTION OF PRIMAQUINE IN MONKEYS [J].

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[4] ANTIMALARIAL ACTIVITY AND INHIBITION OF MONOAMINE OXIDASE-A AND OXIDASE-B BY EXO-ERYTHROCYTIC ANTIMALARIALS - OPTICAL ISOMERS OF PRIMAQUINE, N-ACYLATED CONGENERS, PRIMAQUINE METABOLITES AND 5-PHENOXY-SUBSTITUTED ANALOGS [J].

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ABELL, CW .

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[5]

CLARK AM, 1984, J PHARM SCI, V73, P502, DOI 10.1002/jps.2600730418

[6] PHARMACOKINETICS OF PRIMAQUINE IN MAN - IDENTIFICATION OF THE CARBOXYLIC-ACID DERIVATIVE AS A MAJOR PLASMA METABOLITE [J].

MIHALY, GW ;

WARD, SA ;

EDWARDS, G ;

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BRECKENRIDGE, AM .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 17 (04) :441-446

[7] COMPARISON OF CURATIVE ANTIMALARIAL ACTIVITIES AND TOXICITIES OF PRIMAQUINE AND ITS D AND L ISOMERS [J].

SCHMIDT, LH ;

ALEXANDER, S ;

ALLEN, L ;

RASCO, J .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1977, 12 (01) :51-60

[8] THE PHARMACOKINETICS OF (+)-PRIMAQUINE AND (-)-PRIMAQUINE IN THE ISOLATED PERFUSED-RAT-LIVER PREPARATION [J].

WARD, SA ;

MIHALY, GW ;

NICHOLL, DD ;

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EDWARDS, G .

BIOCHEMICAL PHARMACOLOGY, 1987, 36 (13) :2238-2239

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