CHROMOSOMAL LOCALIZATION OF THE CALLIPYGE GENE IN SHEEP (OVIS-ARIES) USING BOVINE DNA MARKERS

被引：161

作者：

COCKETT, NE

JACKSON, SP

SHAY, TL

NIELSEN, D

MOORE, SS

STEELE, MR

BARENDSE, W

GREEN, RD

GEORGES, M

机构：

[1] TEXAS TECH UNIV,DEPT ANIM SCI & FOOD TECHNOL,LUBBOCK,TX 79409

[2] GENMARK INC,SALT LAKE CITY,UT 84108

[3] CSIRO,DIV TROP ANIM PROD,BRISBANE 4072,AUSTRALIA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1994年 / 91卷 / 08期

关键词：

D O I：

10.1073/pnas.91.8.3019

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A mutation causing muscular hypertrophy, with associated leanness and improved feed efficiency, has been recently identified in domestic sheep (Ovis aries). Preliminary results indicate that an autosomal dominant gene may be responsible for this economically advantageous trait. We have exploited the conservation in sequence and chromosomal location of DNA markers across Bovidae to map the corresponding callipyge locus to ovine chromosome 18 using a battery of bovine chromosome 21 markers. Chromosomal localization of the ovine callipyge locus is the first step toward positional cloning of the corresponding gene.

引用

页码：3019 / 3023

页数：5

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