CANCER-ASSOCIATED TUMOR-MARKERS CA-19-9 AND CA-50 IN PATIENTS WITH PANCREATIC-CANCER WITH SPECIAL REFERENCE TO THE LEWIS BLOOD-CELL STATUS

被引：29

作者：

MASSON, P ^{[1
]}

PALSSON, B ^{[1
]}

ANDRENSANDBERG, A ^{[1
]}

机构：

[1] UNIV LUND HOSP,DEPT CLIN CHEM,S-22185 LUND,SWEDEN

来源：

BRITISH JOURNAL OF CANCER | 1990年 / 62卷 / 01期

关键词：

D O I：

10.1038/bjc.1990.241

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Monoclonal antibodies 19-9 and C-50 were used to assay the cancer associated tumour antigens CA 19-9 and CA-50 in plasma from patients with confirmed pancreatic cancer, and related to the blood group and Lewis blood cell status. The plasma expressions of CA 19-9 or CA-50 were similar, including cases where the patients had Lewis phenotype Le (a - b -). However, analyses of both the tumour antigens could be used to differentiate the presence of cancer from its absence in Le (a -b -) individuals. The findings indicate that the targets for the monoclonal antibodies 19-9 and C-50 are similar. The practical implications of these findings are discussed. © The MacMillan Press Ltd., 1990.

引用

页码：118 / 121

页数：4

共 22 条

[1]

DIENST C, 1987, MED KLIN, V82, P45

[2]

GRUBB R, 1951, ACTA PATHOL MIC SC, V28, P61

[3] TISSUE EXPRESSION OF THE TUMOR-MARKER CA-50 IN BENIGN AND MALIGNANT PANCREATIC LESIONS - A COMPARISON WITH CA-19-9 [J].