Scientific Opinion on the safety assessment of the substance, polyglycerol, CAS No 25618-55-7, for use in food contact materials

被引：1

作者：

Sundh, Ulla Beckman ^{[1
]}

Binderup, Mona-Lise ^{[1
]}

Bolognesi, Claudia ^{[1
]}

Brimer, Leon ^{[1
]}

Castle, Laurence ^{[1
]}

Di Domenico, Alessandro ^{[1
]}

Engel, Karl-Heinz ^{[1
]}

Franz, Roland ^{[1
]}

Gontard, Nathalie ^{[1
]}

Guertler, Rainer ^{[1
]}

Husoy, Trine ^{[1
]}

Jany, Klaus-Dieter ^{[1
]}

Kolf-Clauw, Martine ^{[1
]}

Leclercq, Catherine ^{[1
]}

Lhuguenot, Jean-Claude ^{[1
]}

Mennes, Wim ^{[1
]}

Milana, Maria Rosaria ^{[1
]}

Pocas, Maria de Fatima Tavares ^{[1
]}

Pratt, Iona ^{[1
]}

Svensson, Kettil ^{[1
]}

Toldra, Fidel ^{[1
]}

Woelfle, Detlef ^{[1
]}

机构：

[1] EFSA, Parma, Italy

来源：

EFSA JOURNAL | 2013年 / 11卷 / 10期

关键词：

polyglycerol; polyglycerine; CAS No 25618-55-7; FCM substance No 01017; food contact materials; safety assessment; evaluation;

D O I：

10.2903/j.efsa.2013.3389

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

This scientific opinion of EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids deals with the safety assessment of the additive polyglycerol with the CAS No 25618-55-7, the FCM substance No 01017 for use as plasticizer at a maximum use level of 6.5 % w/w in polymer blends of aliphatic-aromatic polyesters. Final articles are intended to be used in contact with all type of foods for any time at room temperature. Specific migration from a material containing the maximum requested concentration for polyglycerol was calculated by migration modelling to be up to 50 mg/kg food under contact conditions of 10 days at 40 degrees C. Polyglycerol esters were evaluated by JECFA who established an ADI of 0-25 mg/kg bw, and are listed as a food additive (E 475) at levels between 500 and 10 000 mg/kg in certain foods. Up to 7 % of free glycerol/polyglycerol is allowed in E 475 (i.e. 700 mg/kg). No accumulation of polyglycerol in body tissue was observed in an ADME study. The Panel considered that impurities and glycerol which is authorised as a food contact material substance in Regulation (EU) No 10/2011 without a specific migration limit do not raise a safety concern. The CEF Panel concluded that the substance polyglycerol does not raise a safety concern for the consumer if the substance is only to be used as plasticizer at a maximum use level of 6.5 % w/w in polymer blends of aliphatic-aromatic polyesters in contact with all type of foods for any time at room temperature and below. (C) European Food Safety Authority, 2013

引用

页数：8

共 3 条

[1] Guidelines of the Scientific Committee on Food for the presentation of an application for safety assessment of a substance to be used in food contact materials prior its authorisation, (2001)
[2] Toxicological evaluation of certain food additives with a review of general principles and of specifications, (1974)
[3] Howes D., Wilson R., James C.T., The fate of ingested glycerine esters of condensed castor oil fatty acids [Polyglycerol polyricinoleate (PGPR)] in the rat, Food and Chemical Toxicology, 36, pp. 719-738, (1998)

← 1 →